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PLP-dependent enzymes have been classified into five structural classes known as Fold Type I-V (5): Fold Type I - aspartate aminotransferase family Fold Type II - tryptophan synthase family Fold Type III - alanine racemase family Fold Type IV - D-amino acid aminotransferase family Fold Type V - glycogen phosphorylase family The many biochemical reactions catalyzed by PLP-dependent enzymes are involved in essential biological processes, such as hemoglobin and amino acid biosynthesis, as well as fatty acid metabolism

Influence of Hydration and Electrolyte Supplementation on Incidence and Time to Onset of Exercise-Associated Muscle Cramps. Journal of Athletic Training , vol

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