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However, long-term human safety data from controlled clinical trials is limited

PMID: 259 BanyalATiwariSSharmaAChananaIPatelSKSKulshresthaSet al

It was shown before that supplementation with Ferrostain-1 (FER1), which suppresses the accumulation of lipid hydroperoxides in a catalytic fashion 41 , inhibited cell death induced by RSL3 treatment 13

For a broader overview, see the AJMC article on oral peptides

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Lipid peroxidation-derived aldehydes in OA As the most abundant and toxic lipid peroxidation-derived aldehyde, 4-HNE has been shown to be involved in the development of many disorders such as cardiovascular diseases [57], neurological diseases [58], inflammatory bowel disease [59], diabetes [60], RA [61], and different types of cancer [62,63,64]