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Distinction From Other Mitochondrial Peptides While Humanin primarily protects against cell death in neural and cardiac models, MOTS-C peptide broadly enhances metabolic homeostasis by targeting AMP-activated protein kinase, or AMPK, and antioxidant pathways

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On the one hand, the vital substance protects immune cells from oxidative attacks, and on the other hand it increases the activity of various immune cells (e.g

doi:10.1016/S0140-6736(20)32542-3

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