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Experimental studies conducted in animals over the past two decades consistently demonstrate that disruptions in the light-dark schedule induce inflammatory responses across a range of biological systems, with several findings suggesting potential relevance to BC

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This contrasts sharply with orthobiologic therapies like PRP and mesenchymal stem cell therapies, both of which have been evaluated in multiple randomized controlled trials and large observational studies

Still, lingering attitudes continue to influence whether insurance covers drugs proven to be safe and effective