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GLP-1 medications are typically used as a long-term treatment for weight management

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Importantly, clinical studies typically have indiscriminately tested interventions and have rarely utilised biomarkers or clinical symptoms to identify treatment responders, so the clinical indications are in some cases based on the authors opinion regarding the rationalisation of different management options

K(ATP)-channels and glucose-regulated glucagon secretion

Reluctance also stems from how supplements are regulated or not regulated, says Pradeep Natarajan, M.D., director of preventive cardiology at Massachusetts General Hospital