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It's important to note that endogenous GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), giving it a very short half-life in circulation

Case Example A 42-year-old woman with MTHFR C677T homozygous (TT) presented with elevated homocysteine (18 mol/L), hypertension, and family history of stroke

OCT shows maintained ganglion cell layer thickness

There is no clinical evidence linking GHK-Cu to any serious safety issues

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