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In prodrug design strategies, lysine can be linked to active drug molecules through ester or amide bonds, allowing in vivo esterases or peptidases to release the parent drug in target tissues

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Rotate across at least 3 sites

The Warburg effect, of course, to me is interesting because I don't buy the argument that the Warburg is due to defective mitochondria

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Wu Y, Tibrewal N, Birge RB