The human digestive system quickly breaks down water soluble compounds such as glutathione, so eating glutathione rich foods or taking oral glutathione supplements may not produce any clinically significant results
Glutathione (GSH), being the most powerful of antioxidants, is able to cross the blood-brain-barrier, where it protects against oxidative stress by playing an antioxidative role
Frequency depends on your lab results, symptoms, and goals
Nitric oxide also plays a role in iron trafficking because it mimics the consequences of iron starvation and triggers iron uptake by cells
Supplementation with glutathione has been met with little success as the bioavailability of glutathione is low due its transient transport throughout the cellular network
At the cellular level, it improves calcium handling in muscle cells, supporting faster recovery