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Antioxidant Defense and Redox Balance Glutathione serves as the bodys primary intracellular antioxidant by neutralizing reactive oxygen species (ROS) and other free radicals generated during normal cellular metabolism

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The research was carried out in the laboratory of Stephen Bloom (figure 30), an endocrinologist with a long-standing interest in glucagon as well as obesity and diabetes

The modulatory effects of GGT-mediated prooxidant reactions could contribute to the resistance phenotype of GGT-expressing cancer cells by regulating both signal transduction pathways involved in proliferation/apoptosis balance, as well as by inducing protective adaptations in the pool of intracellular antioxidants

Barba, D., Leon-Sosa, A., Lugo, P., Suquillo, D., Torres, F., Surre, F., et al